It has been a while since the term NAFLD (Non-Alcoholic Fatty Liver Disease) was renamed. MASLD (Metabolic Dysfunction-Associated Statistic Liver Disease), but still many do not understand the difference. We bring you an expert guide to help you know the real reasons behind this condition.
The new name highlights the link between fatty liver disease and metabolic problems, such as obesity, type 2 diabetes, and abnormal cholesterol levels. “Unlike the old name, which focused on the absence of alcohol consumption, MASLD highlights that Metabolic dysfunction is the primary reason. This change removes the stigma attached to the term ‘non-alcohol’, which unfairly suggested alcohol use only as a possible factor,” said Dr Sameer Bhati, Director, STAR Imaging and Path Lab.
He added that it also brings attention to the metabolic roots of the condition, helping healthcare providers better understand, diagnose and treat it.
What makes MASLD different?
The updated term reflects the strong connection between fatty liver disease and metabolic problems. βStudies show that fat around stomach (Abdominal obesity) is a significant risk factor for fat accumulation in the liver, making people 2-3 times more likely to develop fatty liver disease,’ Dr Bhati said.
He further shared that MASLD affects approximately 25 percent of people worldwide, with the rate rising to 50-70 percent in those with type 2 diabetes or obesity. “By focusing on metabolic causes, this new term helps healthcare professionals move from managing symptoms to addressing the underlying problems,” said Dr Bhati.
How is MASLD diagnosed?
Advances in non-invasive tests have made diagnosing MASLD easier and more accurate. These include:
FibroScan: A painless, non-invasive test that measures Fatty liver And stiffness, replacing the need for liver biopsy.
Techniques based on MRI scan and ultrasound: Reliable methods for assessing liver fat and scarring.
Blood test: Common screening methods include ALT, AST and GGT, which indicate liver health.
In addition, researchers are exploring new markers such as CK-18 fragments and ELF (Enhanced Liver Fibrosis) score to further improve the accuracy of diagnosis, noted Dr. Bhati.
Why is it different?
Changes in MASLD have important implications for patient care. Focusing on underlying metabolic problems encourages early diagnosis and targeted treatments such as weight loss, better blood sugar control and cholesterol management, Dr Bhati said.
“These interventions may help reduce the long-term risks of heart disease, liver failure, and cirrhosis. MASLD represents a shift toward a more accurate, compassionate, and patient-centered approach to understanding and treating fatty liver disease as its prevalence continues to increase,” Dr. Bhati said.
Prevention
Certain foods can increase it significantly progressAnd among the worst offenders are fast food and junk food, processed foods, and foods with high sugar content, including red and processed meat, said Dr Punit Singla, director and HOD, Institute of Liver Transplant and HPB Surgery, Marengo Asia Hospital, Gurugram.
limiting Or avoid these foods and opt for a balanced diet of whole grains, fruits, vegetables, and lean protein.
Disclaimer: This article is based on information from the public domain and/or experts we spoke to. Always consult your health practitioner before starting any routine.
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